Thursday, 22 December 2011

40 Things You Should Know – The Science (part 11)

Point 49

Effect of caffeine ingestion after creatine supplementation on intermittent high-intensity sprint performance.

http://www.ncbi.nlm.nih.gov/pubmed/21207054

Abstract

The aim of this study was to investigate the effects of acute caffeine ingestion on intermittent high-intensity sprint performance after 5 days of creatine loading. After completing a control trial (no ergogenic aids, CON), twelve physically active men were administered in a double-blind, randomized crossover protocol to receive CRE + PLA (0.3 g kg(-1) day(-1) of creatine for 5 days then followed by 6 mg kg(-1) of placebo) and CRE + CAF (0.3 g kg(-1) day(-1) of creatine for 5 days and followed by 6 mg kg(-1) of caffeine), after which they performed a repeated sprint test. Each test consisted of six 10-s intermittent high-intensity sprints on a cycling ergometer, with 60-s rest intervals between sprints. Mean power, peak power, rating of perceived exertion (RPE), and heart rates were measured during the test. Blood samples for lactate, glucose, and catecholamine concentrations were drawn at specified intervals. The mean and peak power observed in the CRE + CAF were significantly higher than those found in the CON during Sprints 1 and 3; and the CRE + CAF showed significantly higher mean and peak power than that in the CRE + PLA during Sprints 1 and 2. The mean and peak power during Sprint 3 in the CRE + PLA was significantly greater than that in the CON. Heart rates, plasma lactate, and glucose increased significantly with CRE + CAF during most sprints. No significant differences were observed in the RPE among the three trials. The present study determined that caffeine ingestion after creatine supplements augmented intermittent high-intensity sprint performance.


Caffeine is ergogenic after supplementation of oral creatinemonohydrate.

http://www.ncbi.nlm.nih.gov/pubmed/12439084

Abstract

PURPOSE:

The purpose of this investigation was to assess the acute effects of caffeine ingestion on short-term, high-intensity exercise (ST) after a period of oral creatine supplementation and caffeine abstinence.

METHODS:

Fourteen trained male subjects performed treadmill running to volitional exhaustion (T(lim)) at an exercise intensity equivalent to 125% VO(2max). Three trials were performed, one before 6 d of creatine loading (0.3 g x kg x d(-1) baseline), and two further trials after the loading period. One hour before the postloading trials, caffeine (5 mg x kg(-1)) or placebo was orally ingested in a cross-over, double-blind fashion. Four measurements of rating of perceived exertion were taken, one every 30 s, during the first 120 s of the exercise. Blood samples were assayed for lactate, glucose, potassium, and catecholamines, immediately before and after exercise.

RESULTS:

Body mass increased (P < 0.05) over the creatine supplementation period, and this increase was maintained for both caffeine and placebo trials. There was no increase in the maximal accumulated oxygen deficit between trials; however, total VO(2) was significantly increased in the caffeine trial in comparison with the placebo trial (13.35 +/- 3.89 L vs 11.67 +/- 3.61 L). In addition, caffeine T(lim) (222.1 +/- 48.9 s) was significantly greater (P < 0.05) than both baseline (200.8 +/- 33.4 s) and placebo (198.3 +/- 45.4 s) T(lim). RPE was also lower at 90 s in the caffeine treatment (13.8 +/- 1.8 RPE points) in comparison with baseline (14.6 +/- 1.9 RPE points).

CONCLUSION:

As indicated by a greater T(lim), acute caffeine ingestion was found to be ergogenic after 6-d of creatine supplementation and caffeine abstinence.


Point 50

Fluid, electrolyte, and renal indices of hydration during 11 days of controlled caffeine consumption.

http://www.ncbi.nlm.nih.gov/pubmed/16131696

Abstract

This investigation determined if 3 levels of controlled caffeine consumption affected fluid-electrolyte balance and renal function differently. Healthy males (mean +/- standard deviation; age, 21.6 +/- 3.3 y) consumed 3 mg caffeine . kg(-1) . d(-1). on days 1 to 6 (equilibration phase). On days 7 to 11 (treatment phase), subjects consumed either 0 mg (C0; placebo; n= 20), 3 mg (C3; n = 20), or 6 mg (C6; n = 19) caffeine . kg(-1) . d(-1) in capsules, with no other dietary caffeine intake. The following variables were unaffected (P > 0.05) by different caffeine doses on days 1, 3, 6, 9, and 11 and were within normal clinical ranges: body mass, urine osmolality, urine specific gravity, urine color, 24-h urine volume, 24-h Na+ and K+ excretion, 24-h creatinine, blood urea nitrogen, serum Na+ and K+, serum osmolality, hematocrit, and total plasma protein. Therefore, C0, C3, and C6 exhibited no evidence of hypohydration. These findings question the widely accepted notion that caffeine consumption acts chronically as a diuretic.


Rehydration with a caffeinated beverage during the nonexercise periods of 3 consecutive days of 2-a-day practices.

http://www.ncbi.nlm.nih.gov/pubmed/15467100

Abstract

The purpose of this study was to assess the influence of rehydration with a caffeinated beverage during nonexercise periods on hydration status throughout consecutive practices in the heat. Ten (7 women, 3 men) partially heat- acclimated athletes (age 24 +/-1y, body fat 19.2 +/- 2 %, weight 68.4 +/- 4.0 kg, height 170 +/- 3 cm) completed 3 successive days of 2-a-day practices (2 h/practice, 4 h/d) in mild heat (WBGT = 23 C). The 2 trials (double-blind, random, cross-over design) included; 1) caffeine (CAF) rehydrated with Coca-Cola and 2) caffeine-free (CF) rehydrated with Caffeine-Free Coca-Cola. Urine and psychological measures were determined before and after each 2-h practice. A significant difference was found for urine color for the post-AM time point, F = 5.526, P = 0.031. No differences were found among other variables (P > 0.05). In summary, there is little evidence to suggest that the use of beverages containing caffeine during nonexercise might hinder hydration status.


Caffeine during exercise in the heat: thermoregulation and fluid-electrolyte balance.

http://www.ncbi.nlm.nih.gov/pubmed/19092693

Abstract

PURPOSE:

To investigate the effects of caffeine ingestion on thermoregulation and fluid-electrolyte losses during prolonged exercise in the heat.

METHODS:

Seven endurance-trained ( .VO2max = 61 +/- 8 mL.kg.min) heat-acclimated cyclists pedaled for 120 min at 63% .VO2max in a hot-dry environment (36 degrees C; 29% humidity) on six occasions: 1) without rehydration (NF); 2) rehydrating 97% of sweat losses with water (WAT); 3) rehydrating the same volume with a 6% carbohydrate-electrolytes solution (CES); or combining these treatments with the ingestion of 6 mg caffeine.kg (-1) body weight 45 min before exercise, that is, 4) C(AFF) + NF; 5) C(AFF) + WAT; and 6) C(AFF) + CES.

RESULTS:

Without fluid replacement (NF and C(AFF) + NF), final rectal temperature (T(REC)) reached 39.4 +/- 0.1 degrees C, whereas it remained at 38.7 +/- 0.1 degrees C during WAT (CES and C(AFF)+ WAT; (P < 0.05). Caffeine did not alter heat production, forearm skin blood flow, or sweat rate. However, C(AFF) + CES tended to elevate T(REC) above CES alone (38.9 +/- 0.1 degrees C vs 38.6 +/- 0.1 degrees C; P = 0.07). Caffeine ingestion increased sweat losses of sodium, chloride, and potassium ( approximately 14%; P < 0.05) and enlarged urine flow (28%; P < 0.05).

CONCLUSION:

Caffeine ingested alone or in combination with water or a sports drink was not thermogenic or impaired heat dissipation. However, C(AFF) + CES tended to have a higher T(REC) than CES alone. Caffeine increased urine flow and sweat electrolyte excretion, but these effects are not enough to affect dehydration or blood electrolyte levels when exercising for 120 min in a hot environment.

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